Department of Biology presents
Impact of metabolic stress on lipid metabolism and lipidomic profiles in cancer cells
Guest Speaker: Dr. Nousheen Zaidi
Date: Friday, March 9, 2018
Time: 3:15 pm – 4:15 pm
Venue: 10-301, SBASSE Building, LUMS
Host: Dr. Amir Faisal
Abstract
Lipid metabolism has emerged as an important aspect of cancer cell metabolism and is widely shown to be associated with various malignant processes. Cancer cells within solid tumors are exposed to oxygen- and nutrient-gradients depending on their distance from the nearest blood vessels. Our research group is focused on studying the complex interplay between metabolic stress –induced by oxygen and nutrient deprivation– and lipid metabolism in cancer cells. The data indicates that cancer cells differentially activate and thrive on de novo lipid synthesis pathways under metabolic stress.
Biography
In 2008, Dr. Nousheen Zaidi received her doctoral degree in biochemistry from Tubingen, Germany. After completing her PhD she moved to Albert Einstein College of Medicine, NY for postdoctoral research. In early 2011, Dr. Zaidi joined the Drug Discovery Group, Oncology, Johnson and Johnson, Belgium as a postdoctoral research associate. There she worked on a project related to tumor metabolism. In late 2012, Dr. Zaidi moved to Lahore to join the faculty of the Department of Microbiology and Molecular Genetics, Punjab University. Her lab continues to focus on tumor metabolism. Currently, she is also a Humboldt Fellow at Molecular Cancer Research Centre, Charité, Berlin.
